How do I know I'm FTP-ing 'good' software?

Reputable sites like SimTel and Garbo check uploaded utilities for viruses before making them publicly available. However, it makes sense not to take anything for granted. I'm aware of at least one instance of a virus-infected file being found on a SimTel mirror: you can't scan a newly-uploaded file for a virus your scanner doesn't know about. Good A/V packages include self-checking code, though it's unsafe to depend even on this 100%. Be paranoid: you know it makes sense.... In general, don't run *anything* downloaded from the Internet, BBSs etc. until it's been checked with at least one reputable and up-to-date antivirus scanner.